Indapamide: what it does and why people take it

Indapamide is a thiazide-like diuretic doctors prescribe for high blood pressure and fluid retention. It helps your body shed extra salt and water, and that lowers blood pressure. People often like it because one low dose a day can be enough, but there are a few things you should watch for—especially changes in potassium and sodium.

How indapamide works and who should use it

Indapamide reduces fluid volume by making your kidneys remove more salt and water. That eases strain on your heart and blood vessels. It's commonly used in adults with hypertension and sometimes for swelling (edema). If you have severe kidney failure, certain heart rhythm problems, or are allergic to similar diuretics, your doctor may avoid it.

Typical dosing is either 2.5 mg once daily (standard) or 1.5 mg once daily in a sustained-release form. Your doctor will pick the right form and dose based on your blood pressure and other meds. Take it in the morning so you don’t wake up at night needing the bathroom.

Side effects, interactions, and simple safety steps

Common side effects are dizziness, low potassium (hypokalemia), low sodium (hyponatremia), increased uric acid (which can trigger gout), and mild rises in blood sugar or cholesterol. Low potassium can cause weakness or irregular heartbeat, so it matters.

Important drug interactions: indapamide can raise lithium levels, so combining them needs close monitoring. NSAIDs (like ibuprofen) may reduce its effect. If you take potassium-sparing drugs or supplements, tell your doctor so they can balance electrolytes safely.

Practical checks: have your doctor test blood pressure, kidney function, sodium and potassium within a few weeks of starting or changing the dose. After that, checks usually happen every few months depending on your health. If you feel faint, notice muscle cramps, or have a fast or irregular heartbeat, seek advice fast.

Pregnancy and breastfeeding: diuretics are not usually the first choice in pregnancy. If you are pregnant, planning pregnancy, or breastfeeding, talk with your clinician about safer options.

Tips to make it easier: take your dose in the morning with food, get up slowly from sitting or lying down to avoid dizziness, and avoid sudden large increases in alcohol. Keep a list of all your meds and share it with every provider—this cuts down on bad interactions.

If you worry about low potassium, ask whether dietary changes (bananas, spinach, potatoes) or a low-dose supplement are appropriate. Don’t add potassium supplements on your own without checking with your doctor—too much can be harmful in some cases.

Want to compare indapamide to other options? Ask about thiazide diuretics (like hydrochlorothiazide) or other blood pressure classes such as ACE inhibitors or calcium channel blockers. Each has pros and cons; the best choice depends on your full health picture.

Questions for your doctor: What dose is best for me? How often will you check my blood tests? What side effects should make me call immediately? Bringing these up makes the treatment safer and simpler.